About – BIRTH Lab

About

Lab for Brain Imaging Research at Tsinghua
(BIRTH)

The Lab for Brain Imaging Research at Tsinghua (BIRTH Lab) is committed to contributing to the birth of new tools for brain imaging and new discoveries in neuroscience and brain disease research. It is a part of the Center for Biomedical Imaging Research at Tsinghua and the Beijing Multimodal Medical Imaging Engineering Technology Research Center of the School of Biomedical Engineering at Tsinghua University. BIRTH Lab was founded in 2023. Its founder and current director is Dr. Qiyuan Tian, an Assistant Professor and a doctoral supervisor of the School of Biomedical Engineering at Tsinghua University and a Junior Fellow of the International Society for Magnetic Resonance in Medicine.

BIRTH Lab is dedicated to the research and development of new MRI, brain imaging and image computing techniques, especially diffusion and functional MRI, multimodal imaging, deep learning-based image computing methods, and the application and translation of these new methods in neuroscience and brain disease research as well as the diagnosis and treatment of brain diseases. The research lies at the interface of biomedical imaging, brain imaging, neuroscience, computer vision, and machine learning.

Research Directions

弥散及功能磁共振成像的信号处理、建模与分析

基于深度学习的脑成像加速、图像计算及脑疾病智能诊断

复杂脑微观结构成像

脑网络重建、分析与应用

基于磁共振影像的神经外科手术导航

弥撒磁共振成像的生物学准确性验证

Representative Works

Li ZY, Fan Q, Bilgic B, Wang G, Polimeni JR, Huang SY, Tian Q. Diffusion MRI Data Analysis Assisted by Deep Learning Synthesized Anatomical Images. Medical Image Analysis. 2023; 102744.

Tian Q, Li Z, Fan Q, Polimeni JR, Bilgic B, Salat DH, Huang SY. SDnDTI: Self-supervised Deep Leaning-based Denoising for Diffusion Tensor MRI. NeuroImage, 2022; 119033.

Tian Q, Zaretskaya N, Fan Q, Ngamsombat C, Bilgic B, Polimeni JR, Huang SY. Improved Cortical Surface Reconstruction using Sub-millimeter Resolution MPRAGE by Image Denoising. NeuroImage, 2021; 233: 117946.

Tian Q, Bilgic B, Fan Q, Zaretskaya N, Fultz NE, Ohringer NA, Chaudhari AS, Hu Y, Ngamsombat C, Witzel T, Setsompop K, Polimeni JR, Huang SY. Improving In Vivo Human Cerebral Cortical Surface Reconstruction using Data Driven Super-resolution. Cerebral Cortex, 2021; 31 (1): 463-482.

Tian Q, Bilgic B, Fan Q, Ngamsombat C, Liao C, Hu Y, Witzel T, Setsompop K, Polimeni JR, Huang SY. DeepDTI: High-fidelity Six-direction Diffusion Tensor Imaging using Deep Learning. NeuroImage, 2020; 219: 117017.

Tian Q, Wintermark M, Elias WJ, Ghanouni P, Halpern CH, Henderson JM, Huss DS, Goubran M, Thaler C, Airan R, Zeineh M, Pauly KB, McNab JA. Diffusion MRI Tractography for Improved Transcranial MRI-guided Focused Ultrasound Thalamotomy Targeting for Essential Tremor. NeuroImage: Clinical, 2018; 19: 572-580.

Tian Q, Rokem A, Folkerth RD, Nummenmaa A, Fan Q, Edlow BL, McNab JA. Q-Space Truncation and Sampling in Diffusion Spectrum Imaging. Magnetic Resonance in Medicine, 2016; 76 (6): 1750-1763.

Facilities and Resources